Research of the development of anemia in thyroid dysfunctions with the restoration of euthyroidism

Abstract

The research objective is to relate the development of anemia in thyroid dysfunctions and in the restoration of euthyroidism in patients from a University Hospital in the Southern Region of Brazil. We analyzed 152 medical records of patients with a report of the diagnosis of thyroid dysfunction treated from January 1, 2011 to November 30, 2018, selected according to the various ICD-10 of thyroid dysfunction. The results were obtained by analyzing the medical records of the research participants. Restoration of euthyroidism was observed in 38% of participants. The frequency of anemia was 41.26%, 46.8% in patients diagnosed with hypothyroidism and 32.6% in patients with hyperthyroidism. Resolution of anemia was observed in 36% of anemic participants. In both disorders, hematological data demonstrate that anemia among study participants is normocytic and normochromic and that normalization of thyroid hormone levels plays a key role in the resolution of anemia. The normalization of hormone levels seems to have a positive impact on the resolution of anemia, since thyroid hormones play a role not only on erythropoiesis, but also on iron metabolism.